Description
INTRODUCTION ABOUT NEUROKEM M CAPSULE
NEUROKEM M CAPSULE is a combination of Pregabalin and Methylcobalamin which belongs to the group of medicines called Anticonvulsants and Vitamin-B complex respectively. NEUROKEM M CAPSULE is indicated for the management of neuropathic pain in adults. Neuropathic pain is a chronic painful condition caused by damage or disease affecting the somatosensory (sense of touch) nervous system (such as lesion or disease of spinal cord and/or brain).
It can also be caused by prolonged diabetes mellitus, infectious diseases (such as HIV infection or leprosy), chemotherapy, auto-immune disease (Ex. Guillain-Barre syndrome) or by other metabolic dysfunctions. Symptoms include shooting, burning or stabbing pain, tingling and numbness, spontaneous pain (pain without stimulus) or pain caused by normal daily activities that are typically not painful (such as brushing your hair, being in cold temperatures or rubbing against something). Do not stop taking NEUROKEM M CAPSULE without consulting your doctor as it could precipitate withdrawal symptoms such as headache, insomnia (lack of sleep), nausea, pain, diarrhea, flu syndrome, anxiety, nervousness, depression, convulsion, excessive sweating, dizziness and physical dependence.
NEUROKEM M CAPSULE has high potential to cause addiction and therefore caution should be exercised among patients who already has a history of substance abuse. NEUROKEM M CAPSULE can cause suicidal ideation in some individuals and therefore appropriate management should be considered as soon as the signs emerge. NEUROKEM M CAPSULE is not recommended for use in pregnant or breastfeeding women unless advised by the doctor and in male patients who plan to father a child. Consult your doctor before taking NEUROKEM M CAPSULE. The most common side effects of taking NEUROKEM M CAPSULE are dizziness, sleepiness, headache, dry mouth, mood changes, fluid retention and weight gain. Consult your doctor if any of the side effects worsen.
USES OF NEUROKEM M CAPSULE
- Used to manage neuropathic pain
HOW NEUROKEM M CAPSULE WORKS
NEUROKEM M CAPSULE effectively alleviates the symptoms of various types of neuropathic pain, where Methylcobalamin acts by rejuvenating the damaged neurons by improving the production of myelin (a substance that covers and protects the nerve fibers from damage) and pregabalin acts by interfering with various pain signals travelling through the damaged nerves and the brain, thus leading to a significant pain relief in various neuropathic pain states.
DIRECTIONS FOR USE
Take NEUROKEM M CAPSULE as advised by your physician. Swallow NEUROKEM M CAPSULE with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of NEUROKEM M CAPSULE for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF NEUROKEM M CAPSULE
COMMON
- Dizziness, sleepiness, headache
- Nasopharyngitis (common cold)
- Nausea, vomiting, increased appetite, constipation, diarrhea, flatulence, abdominal distension, dry mouth
- Euphoric mood (feeling excited or pleasurable)
- Confusion, irritability, disorientation
- Insomnia (lack of sleep)
- Decrease in sex drive, erectile dysfunction
- Ataxia (impaired balance or coordination), tremor (shaking)
- Dysarthria (disorder of speech)
- Memory impairment, attention disturbance
- Paresthesia (tingling and numbness in extremities)
- Hypoaesthesia (decreased sense of touch)
- Tiredness
- Blurred vision
- Vertigo (spinning sensation)
- Muscle cramps
- Pain in limbs, joints or back
- Cervical spasm (a sudden, involuntary contraction of a muscle in the neck)
- Peripheral edema
- Fall (accidental injury)
- Weight gain
UNCOMMON
- Abnormally low count of a type of white blood cell (neutrophils)
- Loss of appetite
- Low blood sugar levels
- Hallucination, panic attack, restlessness, agitation, depression
- Elevated mood, aggression, mood swings, depersonalisation, word finding difficulty
- Abnormal dreams, libido increased, anorgasmia, apathy
- Fainting, unresponsiveness (stupor)
- Myoclonus (muscle jerks)
- Loss of consciousness, psychomotor hyperactivity
- Dizziness postural
- Involuntary eye movement
- Cognitive disorder
- Mental impairment
- Hyporeflexia (reduction or absence of normal bodily reflexes)
- Hyperaesthesia (excessive physical sensitivity)
- Burning sensation
- Loss of sensation of taste
- General discomfort
- Visual disturbance, eye swelling
- Eye pain or strain
- Photopsia (presence of flashes of light or floaters in the vision)
- Dry eye
- Lacrimation increased, eye irritation
- Disorder in loudness perception
- Fast or slow heart rate, congestive heart failure
- Increased or decreased blood pressure
- Hot flushes, flushing, peripheral coldness
- Shortness of breath, bleeding from nose
- Cough, nasal congestion
- Stuffy nose, snoring, nasal dryness
- Gastrooesophageal reflux disease, salivary hypersecretion
- Oral numbness
- Rash popular, urticaria, itching
- Excess sweating
- Joint swelling, muscle or neck pain
- Muscle twitching or stiffness
- Urinary incontinence, painful urination
- Sexual dysfunction, ejaculation delayed
- Pain menstruation or breast pain
- Generalised oedema, face oedema, chest tightness, pain
- Fever, thirst, chills, lack of energy
- Decreased weight
RARE
- Disinhibition (a pattern of antisocial, impulsive, norm-violating tendency)
- Convulsions
- Parosmia (a smell disorder)
- Dysgraphia (trouble in writing)
- Heart problems (such as prolonged QT interval, sinus tachycardia or sinus arrhythmia)
- Pulmonary edema (fluid retention in the lungs) and throat tightness
- GI tract problems (such as fluid buildup in stomach, pancreatitis, swollen tongue or dysphagia)
- Cold sweats
- Kidney problems (such as renal failure, oliguria and urinary retention)
- Amenorrhea (lack of menstrual periods)
- Breast discharge or enlargement
- Gynecomastia (breast enlargement in males)
Stop taking NEUROKEM M CAPSULE and contact your doctor immediately if you experience any of the following side effects:
- Severe allergic reactions (such as skin rash, itching, swelling of the face, lips, throat, neck and difficulty in breathing)
- Symptoms of elevated creatine kinase (such as unexplained muscle pain, tenderness or weakness, accompanied by malaise or fever)
- Rhabdomyolysis (severe muscle injury)
- Suicidal ideation or behavior
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