Description
INTRODUCTION ABOUT ADGABA AT 100 TABLET
ADGABA AT 100 TABLET is a combination of Amitriptyline and Gabapentin which belongs to the group of medicines called Tricyclic Antidepressants and Antiepileptics. It is used in the management of neuropathic pain in adults. Neuropathic pain is a long-term weakness, numbness or pain caused by damage to the nerves in hands and legs characterized by a feeling of hot, burning, throbbing, shooting, sharp, tingling, numbness.
ADGABA AT 100 TABLET is not recommended for use in patients with severe liver disease and heart problems and it should be used with caution in patients having kidney problems or undergoing haemodialysis. Do not stop taking ADGABA AT 100 TABLET suddenly, as this may lead to increased risk of seizure.
ADGABA AT 100 TABLET is not recommended for use in pregnant woman especially during the last few months of the pregnancy. Do not take ADGABA AT 100 TABLET if you are breast-feeding as it may pass through breast milk to the baby. Consult your doctor for advice before taking it.
ADGABA AT 100 TABLET is not recommended for use in children and adolescents below 18 years of age and should be used with caution in elderly patients aged 65 years and above. Consult your doctor for advice before taking ADGABA AT 100 TABLET.
The most common side effects of taking ADGABA AT 100 TABLET are dizziness, drowsiness, muscle pain, nausea, vomiting and stomach pain. Consult your doctor if any of these side effect worsens.
USES OF ADGABA AT 100 TABLET
- Manage neuropathic pain (long term pain caused by damage to the nerves) in adults
HOW ADGABA AT 100 TABLET WORKS
ADGABA AT 100 TABLET works effectively in reducing the neuropathic pain where Amitriptyline effects are related to its mood-altering activities which acts by increasing the concentration of the neurotransmitters called serotonin and norepinephrine as these substances are found to be low in the anxiety patients and Gabapentin acts by blocking the pain signals travelling through the damaged nerves and the brain and hence manages nerve pain.
DIRECTIONS FOR USE
Take ADGABA AT 100 TABLET as advised by your physician. Swallow ADGABA AT 100 TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. Do not stop taking ADGABA AT 100 TABLET without consulting your doctor.
SIDE EFFECTS OF ADGABA AT 100 TABLET
COMMON
- sleepiness/drowsiness, dizziness, lack of coordination, tiredness
- dizziness while standing up (orthostatic hypotension)
- irregular or fast heartbeat, heart block
- eating disorder characterized by low body weight, increased appetite
- anger, nervousness, difficulty with thinking, confusion, mood changes, depression, anxiety
- jerky movements, loss of memory, tremor, headache, sensitive skin, decreased sensation (numbness), unusual eye movement, increased, decreased or absent reflexes, difficulty with speaking and coordination, difficulty sleeping
- blurred vision, double vision
- feeling of spinning (vertigo)
- high blood pressure
- difficulty in breathing, sore throat, cough, dry and congested nose
- vomiting, nausea
- problems with teeth, inflamed gums
- stomach pain, diarrhea, indigestion, constipation, flatulence, dry mouth or throat
- facial swelling, bruises, rash, itching, acne
- muscles and joint pain, back pain, muscle twitching
- difficulties with erection (impotence) in male
- swelling in the legs and arms, weakness, pain, feeling unwell, difficulty with walking
- increase in weight
- rhythmic shaking movements of body parts
- excessive sweating (anxiety)
- slurred or slow speech
- agitation (anxiety)
- sexual disturbances
- disturbance in attention
- altered taste sensation
- dilated pupils
UNCOMMON
- allergic reaction such as hives
- decreased movements
- difficulty in swallowing
- swelling of the face, limbs and trunk
- excitement, nightmares
- fits, ringing in ears
- nettle rash (urticaria)
- difficulties passing urine
- increased breast milk production or its outflow without breast feeding
- increased pressure in the eyeball
RARE
- loss of consciousness
- decreased appetite
- delirium (especially in elderly patients), hallucinations
- swelling of the salivary glands
- hair loss
- increased sensitivity to sunlight
- breast enlargement in men
- weight loss
Stop taking ADGABA AT 100 TABLET and contact your doctor immediately if you experience any of the following side effects:
- swelling of the skin, lips and face
- rash and redness and/or hair loss
- signs of acute pancreatitis such as nausea and vomiting, persistent stomach pain
- breathing problems, swollen glands
- severe weakness, unusual bruising or bleeding
- frequent infections, muscle pain
- hives (nettle rash), facial swelling due to allergies (Quincke’s oedema or angioedema), difficulty in breathing, severe dizziness with very fast heartbeat and sweating
- blistering of the skin and rapid deterioration of general condition, peeling of skin (including slight bleeding) of eyes, nose, mouth/ lips or genitals (Stevens Johnson-Syndrome, Lyell-Syndrome, Erythema multiforme) and sensitivity to light
- eye pain, intermittent blurred vision, rainbow vision
- jaundice (yellowing of the skin or white of the eyes)
- persistent sore throat and fever
- suicidal thoughts
HOW TO MANAGE SIDE EFFECTS
Nausea or Vomiting:
Take ADGABA AT 100 TABLET with or just after meals. Stick to simple meals. Try to avoid oil rich or spicy foods, sugary snacks and drinks. Try to drink liquid slowly along with your meals or in between meals. Consult your doctor if the symptom worsens.
Dizziness:
Lie or sit down immediately when you feel dizzy. If you’re feeling severe episode of spinning (vertigo), lie in a dark and quite place with eyes closed. Try to avoid vehicle driving. Discuss with your doctor if the symptom worsens.
Headache:
Apply hot or cold-water bag on your head. Try to take rest in a quiet and dark room. Drink tea or coffee. Massage on scalp or head with mild pressure. Consult your doctor if the symptom worsens.
Dry mouth:
Dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free hard candies to stimulate the flow of saliva. Sip water at regular intervals of time. Do not use mouthwashes that contain alcohol because they can be drying. Consult your doctor if the symptom worsens.
Stomach pain:
Try to rest and relax. Try to have smaller and frequent meals. Keep a heat pad on your stomach. Talk to your if the symptoms does not improve.
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