AXONGEN TAB

Axongen Tablet 10 is used to manage these conditions:

• Neuropathic pain caused by nerve damage or dysfunction

• Diabetic peripheral neuropathy, a type of nerve damage due to diabetes

• Post-herpetic neuralgia, a painful condition that can occur after shingles

• Trigeminal neuralgia, a facial pain disorder

• Sciatica and other nerve-related pain conditions

• Pain resulting from spinal cord injury

• Multiple sclerosis, an immune disease

• Chemotherapy-induced neuropathy, a side effect of cancer treatment

  Directions for Use of Axongen Tablet 10

  Here’s how you should take Axongen Tablet 10:

  • Swallow the tablet whole with a glass of water.

  • Avoid crushing or breaking the tablet.

  • It’s not advisable to stop taking this medicine abruptly without speaking to your doctor first. 

    Route of Administration

    Axongen Tablet 10 is taken orally.

    Side Effects of Axongen Tablet 10

    Axongen Tablet 10 might result in the following side effects:

    • Dizziness

    • Drowsiness

    • Headache

    • Dry mouth

    • Constipation

    Managing the Side Effects:

    Most side effects are temporary, usually mild, and resolve upon stopping the use of Axongen Tablet 10. However, if you experience adverse side effects or worsening of any symptoms, please consult your doctor.

    Here are some management tips for a couple of common side effects:

    • Dizziness: If you find that taking this medicine causes dizziness, you can consider taking it at bedtime to minimise daytime disruptions.

    • Constipation: If this medicine causes constipation, consume plenty of water and fibre-rich food.

      How Axongen Tablet 10 Works?

      Axongen Tablet 10 contains two active components:

      • Methylcobalamin (1500 mcg): Also known as Vitamin B12, methylcobalamin helps properly function the brain and nervous system. It performs a key role in DNA and protein synthesis, which promotes nerve regeneration and reduces neurotoxicity.

      • Pregabalin (75 mg): It is an anticonvulsant medication that affects the central nervous system. It binds to calcium channels in the brain, reducing the release of neurotransmitters that cause excitation. This action helps reduce the symptoms of neuropathic pain.

      Both ingredients work together synergistically to manage neuropathic pain. While methylcobalamin aids in repairing damaged nerves, pregabalin helps in reducing the pain signals sent by these nerves.

      Safety Measures & Warnings

      Pregnancy

      Caution is advised while taking Axongen Tablet 10 if you are pregnant. It is best to consult your doctor before taking this medicine.

      Breastfeeding

      Axongen Tablet 10 is passed into human milk. Exercise caution and consult your doctor if you are breastfeeding.

      Alcohol

      Avoid consuming alcohol while on Axongen Tablet 10, as it may increase the risk of side effects like dizziness and drowsiness.

      Liver

      It’s advisable to discuss liver concerns with your doctor before starting treatment with Axongen Tablet 10 as this medicine may impact liver function.

      Kidney

      Caution is advised before using Axongen Tablet 10 if you have a history of kidney. Consult your doctor before taking this medicine.

      Using Machines & Driving

      Caution is recommended as Axongen Tablet 10 can cause dizziness and drowsiness, which could impact your ability to drive or operate machinery.

      Allergy

      Axongen Tablet 10 is contraindicated if you are allergic to methylcobalamin and pregabalin, which are ingredients in this medicine.

      Children

      Axongen Tablet 10 should not be given to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

      Older Patients

      Older patients should take Axongen Tablet 10 under medical supervision, as they could be more sensitive to its side effects. Caution is advised for patients over 70 years of age.

      Interactions of Axongen Tablet 10

      • Drug-Drug Interactions

      Axongen Tablet 10 interacts with medicines:

      • Central Nervous System (CNS) depressants: Medications that slow CNS activity may amplify the sedative effects of Axongen Tablet 10, which could lead to increased drowsiness and potential respiratory depression. Examples include opioids like morphine and codeine, benzodiazepines like alprazolam and diazepam, and barbiturates like phenobarbital and primidone.

      • Medications for diabetes such as Thiazolidinediones: Taking diabetes medications such as pioglitazone or rosiglitazone with Axongen Tablet 10 may result in weight gain and fluid buildup, which can exacerbate heart failure conditions in some patients.

      • Drug-Food Interactions

      Axongen Tablet 10 does not have significant interactions with specific foods. You can take this medicine with or without food, depending on your preference.

      • Drug-Disease Interactions

      Axongen Tablet 10 interacts with diseases:

      • Kidney impairment: If you have severe kidney problems, you should exercise caution when taking Axongen Tablet 10, as pregabalin is primarily eliminated from the body through the kidneys.

      • Heart failure: Patients with heart failure should be monitored closely while taking Axongen Tablet 10, as it can cause peripheral oedema (swelling of the hands, ankles, and feet) and weight gain, which might worsen their condition.

        Dosage of Axongen Tablet 10

        • Daily Dose

        The daily dose of Axongen Tablet 10 should be taken as directed by your doctor. The dosage may vary depending on the severity of your condition and how you respond to the medication. Always adhere to the prescribed dosage.

        • Over Dose

        In case of an accidental overdose of Axongen Tablet 10, you may experience symptoms such as restlessness and confusion. If you notice these or other symptoms, inform your doctor promptly.

        • Missed Dose

        If you happen to miss a dose of Axongen Tablet 10, take it when you remember. However, if it’s nearly time for your next dose, skip the missed one and continue with your regular schedule. It’s important not to alter your dosage without consulting your doctor.

        Storage

        • Store Axongen Tablet 10 at room temperature, ideally below 25°C.

        • Protect the medicine from moisture to maintain its effectiveness.

        • Keep this medicine out of the reach of children.

        • Check the expiration date on the box and use the medicine before that date.

          Diet and Lifestyle Advice

          • Regular physical activity can help manage neuropathic pain. Try gentle exercises like walking or swimming, but always consult the doctor before starting a new fitness regime.

          • Limit your alcohol intake, as it can interfere with the working of Axongen Tablet 10 and exacerbate the symptoms of neuropathic pain.